Description

1-(4-Methylphenyl)Cyclobutanecarboxylic Acid is a specialized organic compound featuring a cyclobutane ring fused with a para-methyl substituted phenyl group, serving as a valuable synthetic intermediate. This compound is crucial for constructing complex molecular architectures in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for applications in catalysis, ligand synthesis, and as a building block for active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its unique steric and electronic properties.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Academic & Industrial R&D: A versatile scaffold for methodological chemistry research and discovery chemistry in corporate and institutional laboratories.

Basic Information

Item	Details
Product Name	1-(4-Methylphenyl)Cyclobutanecarboxylic Acid
CAS No.	50921-38-5
Molecular Formula	C12H14O2
Molecular Weight	190.24 g/mol
Synonyms	4-Methyl-α-phenylcyclobutanemethanol carboxylic acid; p-Tolylcyclobutanecarboxylic Acid; 1-(p-Tolyl)cyclobutanecarboxylic Acid; 1-(4-Methylphenyl)cyclobutanecarboxylic acid; Cyclobutanecarboxylic acid, 1-(4-methylphenyl)-; 1-(4-Methylphenyl)cyclobutane-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(4-Methylphenyl)Cyclobutanecarboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and other relevant spectroscopic methods. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.