Description

1-Chloro-3-Methoxypropan-2-One is a versatile and reactive organic building block, primarily valued for its role as a key intermediate in the synthesis of more complex molecules. Its bifunctional nature, featuring both a chloro and a methoxy group adjacent to a ketone, makes it an essential reagent for introducing specific moieties in pharmaceutical and agrochemical research. This compound is particularly sought after by R&D chemists and process development teams in the fine chemical, pharmaceutical, and specialty chemical industries for constructing heterocycles and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of various active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring specific ether and ketone functionalities.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where its reactive sites allow for the creation of complex molecular architectures.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, including dyes, pigments, and performance materials.
• Research & Development: Employed in academic and industrial laboratories for method development and the exploration of new synthetic pathways in organic chemistry.
• Chemical Derivatization: Useful for modifying polymers or other materials by introducing methoxypropyl or chloropropanone groups to alter physical or chemical properties.

Basic Information

Product Name	1-Chloro-3-Methoxypropan-2-One
CAS No.	50918-61-1
Molecular Formula	C4H7ClO2
Molecular Weight	122.55 g/mol
Synonyms	3-Methoxy-1-chloro-2-propanone; 1-Chloro-3-methoxyacetone; 3-Methoxy-1-chloroacetone; Chloromethoxyacetone; 2-Propanone, 1-chloro-3-methoxy-; Methoxychloroacetone
EINECS	Contact for details

Quality Control

Our 1-Chloro-3-Methoxypropan-2-One is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including assay by GC/HPLC and identification by FT-IR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We are committed to meeting the rigorous standards required for GMP and ISO-guided manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area away from incompatible materials such as strong acids, bases, and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	≤ 2.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.