Description

4'-Chlorophenyl 2-Acetamido-3,4,6-Tetra-o-Acetyl-2-Deoxy-β-D-Glucopyranoside is a key protected glycoside intermediate, specifically a derivative of N-acetylglucosamine, designed for advanced synthetic chemistry. This compound is critical for researchers and manufacturers requiring high-purity, structurally defined building blocks for the synthesis of complex oligosaccharides and glycoconjugates. It is primarily utilized in pharmaceutical R&D for the development of novel therapeutics, including carbohydrate-based drugs and diagnostic agents, as well as in biochemical studies exploring glycosylation processes.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of complex carbohydrate-based active pharmaceutical ingredients (APIs) and prodrugs.
• Glycoconjugate Synthesis: Used in the preparation of glycoproteins, glycolipids, and other glycoconjugates for biological and immunological research.
• Oligosaccharide Assembly: Acts as a protected glycosyl donor or acceptor in automated and solution-phase oligosaccharide synthesis.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies related to glycosyltransferases and glycosidases.
• Diagnostic Reagent Development: Utilized in creating labeled probes and standards for carbohydrate analysis and detection assays.
• Chemical Biology Tool: Facilitates the study of carbohydrate-protein interactions and cell surface recognition events.

Basic Information

Item	Details
Product Name	4'-Chlorophenyl 2-Acetamido-3,4,6-Tetra-o-Acetyl-2-Deoxy-β-D-Glucopyranoside
CAS No.	50729-97-0
Molecular Formula	C22H26ClNO10
Molecular Weight	499.90 g/mol
Synonyms	1-O-(4-Chlorophenyl)-2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranoside; 4'-Chlorophenyl 2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-β-D-glucopyranoside; N-Acetyl-4'-chlorophenyl-3,4,6-tri-O-acetyl-β-D-glucosaminide; β-D-Glucopyranoside, 4'-chlorophenyl 2-(acetylamino)-2-deoxy-3,4,6-tri-O-acetyl-; Protected N-Acetylglucosamine derivative; GlcNAc(β1-O)Ph(4-Cl) peracetate
EINECS	Contact for details

Quality Control

Our 4'-Chlorophenyl 2-Acetamido-3,4,6-Tetra-o-Acetyl-2-Deoxy-β-D-Glucopyranoside is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and chiral analysis to ensure stereochemical integrity. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical parameters to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	-20° to -25° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.