Description

C-(2,2-Dimethyl-Tetrahydro-Pyran-4-Yl)-Methylamine is a versatile chiral amine building block characterized by its tetrahydro-2H-pyran scaffold with geminal dimethyl substitution. This compound matters for its role as a key intermediate in the synthesis of complex molecules, offering a rigid, sterically defined structure that is crucial for modulating biological activity and physical properties. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing active pharmaceutical ingredients (APIs), agrochemicals, and advanced material science applications.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its structural motif can contribute to enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and functional materials requiring specific stereochemical configurations.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up services for the fine chemical industry.

Basic Information

Product Name	C-(2,2-Dimethyl-Tetrahydro-Pyran-4-Yl)-Methylamine
CAS No.	50675-25-7
Molecular Formula	C8H17NO
Molecular Weight	143.23 g/mol
Synonyms	4-(Aminomethyl)-2,2-dimethyltetrahydro-2H-pyran; (2,2-Dimethyltetrahydro-2H-pyran-4-yl)methanamine; 2,2-Dimethyl-4-(aminomethyl)tetrahydropyran; 4-(Aminomethyl)-2,2-dimethyltetrahydropyran; 2,2-Dimethyltetrahydropyran-4-ylmethylamine; (2,2-Dimethyltetrahydro-2H-pyran-4-yl)methylamine; 50675-25-7; 4-(Aminomethyl)-2,2-dimethyloxane
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for fine chemical intermediates. We employ advanced analytical techniques including HPLC, GC, and NMR to verify identity, purity, and chiral integrity. Certificates of Analysis (COA) are available upon request, detailing batch-specific results. Our quality management system supports development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.