Description

4-(N,n-Dimethyl-n-(2-Hydroxyethyl))Ammonium-2,2,6,6-Tetramethylpiperidine-1-Oxyl Chloride is a stable nitroxide radical compound, specifically a TEMPO derivative with a quaternary ammonium group. This unique structure makes it a highly effective and versatile polymerization regulator and spin label for advanced research and industrial applications. It is essential for industries requiring precise control over polymer molecular weight and architecture, as well as for biophysical studies. Key users include manufacturers of specialty polymers, adhesives, coatings, and research institutions in materials science and biochemistry.

Application

• Nitroxide-Mediated Polymerization (NMP): Acts as a controlling agent for the synthesis of polymers with well-defined architectures, such as block copolymers, in the production of advanced plastics, adhesives, and coatings.
• Spin Labeling in Biochemistry: Used as a paramagnetic probe in Electron Paramagnetic Resonance (EPR) spectroscopy to study protein dynamics, membrane fluidity, and macromolecular structure.
• Polymer Stabilization: Functions as a radical scavenger and antioxidant to inhibit thermal and oxidative degradation during polymer processing and in final products.
• Organic Synthesis: Serves as a catalyst or mediator in selective oxidation reactions and other radical-based synthetic transformations.
• Surface Modification: Utilized to graft polymer brushes onto surfaces for creating functional coatings with specific properties like hydrophilicity or anti-fouling characteristics.
• Research & Development: A critical reagent for academic and industrial R&D focused on controlled radical polymerization techniques and advanced material design.

Basic Information

Product Name	4-(N,n-Dimethyl-n-(2-Hydroxyethyl))Ammonium-2,2,6,6-Tetramethylpiperidine-1-Oxyl Chloride
CAS No.	50669-92-6
Molecular Formula	C13H28ClN2O2+
Molecular Weight	279.83 g/mol
Synonyms	4-Hydroxy-2,2,6,6-tetramethylpiperidin-1-oxyl, trimethylammonium chloride; TEMPO-Choline Chloride; 4-(N,N-Dimethyl-N-(2-hydroxyethyl)ammonio)-2,2,6,6-tetramethylpiperidine-1-oxyl chloride; 4-[(2-Hydroxyethyl)dimethylammonio]-2,2,6,6-tetramethylpiperidine-1-oxyl chloride; Choline-TEMPO Chloride; N,N-Dimethyl-N-(2-hydroxyethyl)-4-amino-2,2,6,6-tetramethylpiperidine-1-oxyl chloride; (1-Oxyl-2,2,6,6-tetramethylpiperidin-4-yl)trimethylammonium chloride (hydroxyethyl variant); Stable free radical nitroxide.
EINECS	Contact for details

Quality Control

Our production of 4-(N,n-Dimethyl-n-(2-Hydroxyethyl))Ammonium-2,2,6,6-Tetramethylpiperidine-1-Oxyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and high performance in sensitive applications like polymerization and spectroscopy. Each lot undergoes comprehensive analysis, including assay by HPLC, verification of radical purity by EPR, and control of key impurities. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent degradation from atmospheric moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Identification (EPR)	Positive for stable nitroxide radical
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
EPR Spectroscopy	Single radical species, typical triplet signal

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.