Description

Methanesulfonic Acid,(1S)-1-Methylpropyl Ester is a chiral ester derivative of methanesulfonic acid, serving as a versatile building block and reagent in advanced organic synthesis. Its value lies in its role as a chiral auxiliary or protecting group, enabling the stereoselective construction of complex molecules with high enantiomeric purity. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where precise control over molecular chirality is critical for developing active ingredients.

Application

• Pharmaceutical Intermediate: Used in the stereoselective synthesis of active pharmaceutical ingredients (APIs), particularly for constructing chiral centers.
• Asymmetric Synthesis: Acts as a chiral reagent or auxiliary in catalytic and stoichiometric asymmetric reactions.
• Agrochemical Research: Employed in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a key intermediate for specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & R&D: A valuable tool in university and corporate research laboratories for methodological development in organic chemistry.
• Protecting Group Chemistry: Can be utilized to protect functional groups temporarily during multi-step synthetic sequences.

Basic Information

Product Name	Methanesulfonic Acid,(1S)-1-Methylpropyl Ester
CAS No.	50599-13-8
Molecular Formula	C6H14O3S
Molecular Weight	166.24 g/mol
Synonyms	(S)-sec-Butyl methanesulfonate; (1S)-1-Methylpropyl methanesulfonate; (S)-Butan-2-yl methanesulfonate; L-sec-Butyl methanesulfonate; (S)-(-)-sec-Butyl methanesulfonate; Methanesulfonic acid sec-butyl ester, (S)-; (S)-sec-Butyl mesylate
EINECS	Contact for details

Quality Control

Our production of Methanesulfonic Acid,(1S)-1-Methylpropyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric excess (ee). Each lot is characterized by advanced analytical techniques including chiral HPLC, NMR, and GC-MS. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are provided with every shipment, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere if necessary after opening to maintain purity and prevent hydrolysis.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.