Description

Dimethoxymethylium Hexafluorophosphate is a highly reactive, crystalline salt primarily used as a powerful methylating and methoxymethylating agent in organic synthesis. Its value lies in its ability to efficiently transfer the dimethoxymethyl (CH(OCH3)2+) cation, a key step in constructing complex molecular architectures under mild conditions. This reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, where precise functional group manipulation is critical. The compound, identified by CAS No. 50318-32-6, is a cornerstone for developing active pharmaceutical ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for introducing methoxymethyl (MOM) protecting groups for alcohols and phenols, and for methylation reactions in API development.
• Agrochemical Manufacturing: Used in the synthesis of herbicides, fungicides, and insecticides that require specific methyl or methoxymethyl functionalities.
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and photoinitiators where controlled methylation is necessary.
• Polymer & Material Science: Acts as a cationic initiator or modifying agent in the synthesis of specialized polymers and advanced organic materials.
• Academic & R&D Laboratories: A valuable tool for methodological development and the synthesis of novel organic compounds in research settings.
• Peptide Chemistry: Can be utilized for selective modification of amino acid side chains during peptide synthesis.

Basic Information

Product Name	Dimethoxymethylium Hexafluorophosphate
CAS No.	50318-32-6
Molecular Formula	C3H9F6O2P
Molecular Weight	222.07 g/mol
Synonyms	Methoxymethyl Dimethyloxonium Hexafluorophosphate; Dimethyl(methoxymethoxy)oxonium Hexafluorophosphate; (Dimethoxymethyl)oxonium Hexafluorophosphate; Dimethoxymethyl Hexafluorophosphate; CH(OCH3)2+ PF6-; Dimethoxymethyleneoxonium Hexafluorophosphate; MOM-PF6
EINECS	Contact for details

Quality Control

Our Dimethoxymethylium Hexafluorophosphate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot undergoes comprehensive analysis, including assay by NMR or titration, identification by FT-IR, and quantification of key impurities. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with our stringent in-house specifications. For customers with specific purity requirements, custom synthesis and analytical validation services are available.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). Keep the container tightly sealed under an inert atmosphere (argon or nitrogen) to prevent decomposition. Store away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (NMR/Titration)	≥ 98.0 %
Water Content (KF)	≤ 0.5 %
Solubility	Soluble in polar organic solvents (e.g., DCM, ACN)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.