Description

Aminoisobutyric Acid Hydrochloride is the hydrochloride salt of the non-proteinogenic amino acid 2-aminoisobutyric acid, offering enhanced stability and solubility for synthetic applications. This compound serves as a crucial chiral building block and intermediate in the synthesis of complex pharmaceutical molecules and bioactive peptides. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing novel therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the production of active pharmaceutical ingredients (APIs), particularly in peptidomimetics and metabolic modulators.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate the unique, sterically hindered 2-aminoisobutyric acid (Aib) residue, which induces helical conformations.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, fungicides, and plant growth regulators with improved efficacy.
• Biochemical Research: Employed in metabolic pathway studies and as a standard in analytical chromatography for amino acid analysis.
• Fine Chemical Synthesis: A versatile building block for creating specialty chemicals, including ligands for catalysts and components for advanced materials.
• Cosmetic Ingredient Intermediate: Used in the synthesis of certain conditioning agents and skin-active peptides for cosmetic formulations.

Basic Information

Product Name	Aminoisobutyric Acid Hydrochloride
CAS No.	5938-34-1
Molecular Formula	C4H9NO2 • HCl
Molecular Weight	139.58 g/mol
Synonyms	2-Aminoisobutyric Acid Hydrochloride; (Amino-1,1-dimethylethanoic acid) hydrochloride; 2-Methylalanine Hydrochloride; α-Aminoisobutyric Acid HCl; Aib-OH • HCl; 2-Amino-2-methylpropanoic Acid Hydrochloride; DL-2-Aminoisobutyric Acid Hydrochloride; 2,2-Dimethylglycine Hydrochloride
EINECS	227-689-3

Quality Control

Our Aminoisobutyric Acid Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and production. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation and clumping.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.