Description

5-Carboxy-8-Hydroxyquinoline is a versatile quinoline derivative that serves as a key synthetic intermediate and chelating agent. Its bifunctional structure, featuring both carboxylic acid and phenolic hydroxyl groups, provides unique coordination properties and reactivity. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors, where it is used to develop active ingredients, metal scavengers, and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those with metal-chelating or antimicrobial properties.
• Agrochemical Synthesis: Used in the production of advanced fungicides, herbicides, and plant growth regulators.
• Analytical Chemistry Reagent: Acts as a sensitive chromogenic and fluorogenic agent for the spectrophotometric and fluorometric determination of various metal ions (e.g., aluminum, magnesium).
• Metal Chelation & Catalysis: Serves as a ligand for transition metals, forming complexes used in homogeneous catalysis and as models for metalloenzymes.
• Material Science: A precursor for the development of organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Chemical Research: Employed in organic synthesis for the preparation of more complex heterocyclic compounds and functionalized quinolines.

Basic Information

Product Name	5-Carboxy-8-Hydroxyquinoline
CAS No.	5852-78-8
Molecular Formula	C10H7NO3
Molecular Weight	189.17 g/mol
Synonyms	8-Hydroxyquinoline-5-carboxylic acid; 5-Carboxy-8-quinolinol; Oxine-5-carboxylic acid; 5-Carboxy-8-oxyquinoline; 8-Hydroxy-5-quinolinecarboxylic acid; 5-Quinolinecarboxylic acid, 8-hydroxy-; 8-Hydroxy-5-quinoline carboxylic acid
EINECS	227-466-8

Quality Control

Our 5-Carboxy-8-Hydroxyquinoline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR for identification, and loss on drying for moisture content, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.