Description

2-Chloro-N,n-Dimethyl-3-Oxobutyramide is a versatile chlorinated ketoamide compound with significant synthetic utility. It serves as a key reactive intermediate in the production of more complex molecules, particularly in the pharmaceutical and agrochemical sectors. This product is essential for research chemists and process development teams seeking to introduce specific functional groups or build heterocyclic frameworks. Its consistent quality and reliable supply are critical for ensuring the reproducibility of downstream synthesis and manufacturing processes.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing pyridine or other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where its reactive chloro and keto groups enable specific modes of action.
• Organic Synthesis Reagent: Employed in research laboratories for constructing complex organic molecules, including natural product analogs and specialty chemicals.
• Dye and Pigment Manufacturing: Acts as a precursor in the synthesis of certain high-performance dyes and organic pigments.
• Cross-coupling Reactions: Serves as a substrate in palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Chemical Research & Development: A valuable tool for medicinal chemistry and process chemistry teams exploring new synthetic pathways.

Basic Information

Product Name	2-Chloro-N,n-Dimethyl-3-Oxobutyramide
CAS No.	5810-07-1
Molecular Formula	C6H10ClNO2
Molecular Weight	163.60 g/mol
Synonyms	2-Chloro-N,N-dimethylacetoacetamide; 2-Chloro-3-oxo-N,N-dimethylbutyramide; 3-Oxobutyramide, 2-chloro-N,N-dimethyl-; N,N-Dimethyl-2-chloroacetoacetamide; Acetoacetamide, 2-chloro-N,N-dimethyl-; 2-Chloro-N,N-dimethyl-3-oxobutanamide; α-Chloro-N,N-dimethylacetoacetamide
EINECS	227-371-6

Quality Control

Our 2-Chloro-N,n-Dimethyl-3-Oxobutyramide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We are committed to consistent quality and supply chain transparency for our global B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are kept tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.