Description

2-(Methylthio)Thiophene is a specialized sulfur-containing heterocyclic compound with the CAS number 5780-36-9, serving as a versatile building block in advanced organic synthesis. Its unique thiophene core functionalized with a methylthio group makes it a critical intermediate for developing high-value materials and active ingredients. This compound is essential for R&D and production teams in the pharmaceutical, agrochemical, and material science sectors seeking to innovate with sulfur chemistry.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides, herbicides, and fungicides, where the thiophene moiety contributes to biological activity.
• Material Science & Organic Electronics: Serves as a precursor for conductive polymers, organic semiconductors, and non-linear optical (NLO) materials due to its electron-rich structure.
• Ligand & Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis, facilitating more efficient and selective chemical transformations.
• Flavor & Fragrance Industry: Acts as a starting material for synthesizing complex sulfur-containing aroma compounds.
• Research & Development: A valuable reagent for academic and industrial research in heterocyclic and organosulfur chemistry.

Basic Information

Product Name	2-(Methylthio)Thiophene
CAS No.	5780-36-9
Molecular Formula	C5H6S2
Molecular Weight	130.23 g/mol
Synonyms	2-Methylthiothiophene; Thiophene, 2-(methylthio)-; Methyl 2-thienyl sulfide; 2-(Methylsulfanyl)thiophene; 2-Thienyl methyl sulfide; 2-Methylmercaptothiophene; 2-(Methylthio)thiophene; 2-Methylthio-thiophene
EINECS	227-300-6

Quality Control

Our 2-(Methylthio)Thiophene is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including GC, HPLC, and NMR for comprehensive characterization and impurity profiling. A Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.580 - 1.590
Density (20°C)	1.15 - 1.20 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.