Description

2-Chloro-Biphenyl-4-Ylamine is a halogenated aromatic amine derivative that serves as a versatile and critical building block in advanced organic synthesis. Its molecular structure makes it a valuable intermediate for creating complex molecules with specific electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting specific receptor sites.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the biphenyl core provides structural stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic semiconductors.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing complex azo dyes and high-performance pigments.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions like Suzuki-Miyaura or Buchwald-Hartwig amination for creating biaryl structures.
• Laboratory Reagent: Used in academic and industrial R&D for method development and exploring new synthetic pathways.

Basic Information

Product Name	2-Chloro-Biphenyl-4-Ylamine
CAS No.	5730-85-8
Molecular Formula	C12H10ClN
Molecular Weight	203.67 g/mol
Synonyms	4-Amino-2-chlorobiphenyl; 2-Chloro-4-aminobiphenyl; 2-Chloro-4-biphenylamine; (2-Chlorophenyl)aniline; 2-Chloro-1,1'-biphenyl-4-amine; Biphenyl-4-ylamine, 2-chloro-; 2-Chloro-4-phenylaniline
EINECS	227-247-5

Quality Control

Our 2-Chloro-Biphenyl-4-Ylamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets precise customer specifications. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting compliance in regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.