Description

Amino-Cyclohexyl-Acetic Acid is a versatile chiral building block and intermediate of significant importance in fine chemical synthesis. Its unique structure, featuring both an amino and a carboxylic acid functional group on a cyclohexyl backbone, makes it a valuable precursor for creating complex molecules with specific stereochemistry. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries. It serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and specialized agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring specific stereoisomers for enhanced activity.
• Peptide Mimetics & Conformationally Restricted Analogues: The cyclohexyl ring provides rigidity, making it valuable for designing peptide mimics and bioactive compounds with improved metabolic stability.
• Ligand & Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis and metal complex formation.
• Fine Chemical & Specialty Chemical Production: Employed in custom synthesis and the manufacture of high-value, low-volume specialty chemicals.
• Biochemical Research: Utilized as a standard or building block in metabolic pathway studies and enzyme inhibition research.

Basic Information

Item	Detail
Product Name	Amino-Cyclohexyl-Acetic Acid
CAS No.	5664-29-9
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	2-Aminocyclohexaneacetic Acid; (1-Aminocyclohexyl)acetic Acid; 1-Aminocyclohexaneacetic Acid; trans-2-Aminocyclohexaneacetic Acid; cis-2-Aminocyclohexaneacetic Acid; Cyclohexylglycine; NSC 163022; ACAA
EINECS	Contact for details

Quality Control

Our Amino-Cyclohexyl-Acetic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, which include data for assay, chiral purity, and specific impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (specify isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.