Description

Bicyclo[2.2.0]Hexa-2,5-Diene, also known as Dewar Benzene, is a highly strained and reactive organic compound with the unique structure of a benzene isomer. This compound matters as a valuable synthetic intermediate and a fascinating subject in theoretical and physical organic chemistry research due to its unusual bonding and high energy content. It is primarily needed by researchers and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors for exploring novel reaction pathways and synthesizing complex molecular architectures.

Application

• Organic Synthesis Intermediate: Serves as a key precursor in the synthesis of complex polycyclic compounds and cage structures.
• Pharmaceutical Research: Used in the development of novel drug candidates and bioactive molecules, leveraging its unique reactivity.
• Material Science: Investigated for the creation of novel polymers and advanced organic materials with specific electronic properties.
• Theoretical & Mechanistic Studies: A fundamental molecule for studying valence isomerization, pericyclic reactions, and strain energy in organic chemistry.
• Agrochemical Development: Employed in the research and synthesis of new active ingredients for crop protection.
• Ligand & Catalyst Design: Utilized as a building block for creating novel ligands and organometallic complexes in catalysis research.

Basic Information

Product Name	Bicyclo[2.2.0]Hexa-2,5-Diene
CAS No.	5649-95-6
Molecular Formula	C6H6
Molecular Weight	78.11 g/mol
Synonyms	Dewar Benzene; Bicyclo[2.2.0]hexa-2,5-diene; 1,2,4,5-Cyclohexatetraene (Dewar form); 2,5-Dihydro-1,3-cyclobutadiene (incorrect but sometimes used); [2.2.0]Bicyclohexa-2,5-diene
EINECS	227-694-9

Quality Control

Our Bicyclo[2.2.0]Hexa-2,5-Diene is produced and handled under strict quality protocols to ensure batch-to-batch consistency and purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as purity (by GC or NMR), identity confirmation, and solvent content. We adhere to cGMP principles where applicable to support our clients in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at recommended temperatures between -20°C to -10°C or as specified on the label to maintain stability and prevent decomposition. Keep away from heat, sparks, and open flames. The container must be kept tightly sealed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid / solution
Identification (IR / NMR)	Conforms to structure
Purity (GC / NMR)	≥ 95% (Typical 97-99%)
Solvent Content (GC)	As per COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.