Description

1,6-Hexane Diisothiocyanate is a bifunctional isothiocyanate compound, a versatile chemical building block prized for its ability to form stable thiourea linkages. This property makes it a critical intermediate for synthesizing polymers, cross-linking agents, and specialty chemicals with enhanced thermal and chemical resistance. It is essential for manufacturers and R&D teams in the polymer, coatings, adhesives, and pharmaceutical intermediate sectors seeking to develop advanced materials.

Application

• Polymer Synthesis: Key monomer for producing polyurethanes, polyureas, and other specialty polymers requiring thiocarbamate linkages.
• Cross-linking Agent: Used to cross-link polymers containing amine groups, improving the mechanical strength, thermal stability, and chemical resistance of coatings, adhesives, and elastomers.
• Pharmaceutical Intermediates: Serves as a building block in the synthesis of active pharmaceutical ingredients (APIs) and drug delivery systems.
• Surface Modification: Functionalizes surfaces (e.g., glass, metals, polymers) by introducing reactive isothiocyanate groups for further conjugation with biomolecules or polymers.
• Bioconjugation Chemistry: Used to covalently link proteins, peptides, or other amine-containing biomolecules in diagnostic and research applications.
• Agricultural Chemicals: Intermediate in the synthesis of certain herbicides, fungicides, and plant growth regulators.

Basic Information

Product Name	1,6-Hexane Diisothiocyanate
CAS No.	5586-70-9
Molecular Formula	C8H12N2S2
Molecular Weight	200.32 g/mol
Synonyms	Hexamethylene Diisothiocyanate; 1,6-Diisothiocyanatohexane; HDI-Thiocyanate; Hexane-1,6-diyl diisothiocyanate; NSC 154891; Bis(6-isothiocyanatohexyl) ether (related); Aliphatic diisothiocyanate
EINECS	226-983-5

Quality Control

Our 1,6-Hexane Diisothiocyanate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including assay by HPLC, identification by FT-IR, and control of key impurities, to ensure it meets stringent specifications for industrial and research applications. A Certificate of Analysis (COA) detailing purity, identity, and physical parameters is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 15-25°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under a dry inert atmosphere (e.g., nitrogen) to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Gravity (20°C)	1.10 - 1.15
Refractive Index (n20D)	1.550 - 1.570

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.