Description

2,5,8,11,14-Pentaoxahexadecan-16-Amine is a specialized polyether amine compound, recognized for its unique hydrophilic linker and terminal amine functionality. This structure is critical for applications requiring water solubility, controlled reactivity, and chain extension in advanced material synthesis. It serves as a valuable building block for researchers and manufacturers in the pharmaceutical, polymer, and specialty chemical industries seeking to modify solubility profiles and introduce reactive sites.

Application

• Pharmaceutical Intermediate: Used in the synthesis of prodrugs, drug conjugates, and active pharmaceutical ingredients (APIs) where a hydrophilic polyethylene glycol (PEG)-like spacer is required.
• Polymer Modification: Acts as a chain extender or cross-linking agent in polyurethane, epoxy, and other polymer systems to introduce flexibility and hydrophilicity.
• Surface Functionalization: Employed to modify surfaces of nanoparticles, quantum dots, and other materials to improve aqueous dispersion and biocompatibility.
• Bioconjugation Linker: Serves as a spacer arm in the conjugation of peptides, proteins, or dyes, helping to reduce steric hindrance.
• Specialty Surfactant Synthesis: A key precursor for creating non-ionic surfactants and emulsifiers with specific solubility properties.
• Research & Development: A versatile reagent in organic synthesis and material science R&D for constructing complex molecular architectures.

Basic Information

Product Name	2,5,8,11,14-Pentaoxahexadecan-16-Amine
CAS No.	5498-83-9
Molecular Formula	C11H25NO5
Molecular Weight	251.32 g/mol
Synonyms	2,5,8,11,14-Pentaoxahexadecan-16-amine; 16-Amino-2,5,8,11,14-pentaoxahexadecane; 4,7,10,13,16-Pentaoxanonadecan-1-amine; O,O'-Bis(2-aminoethyl)nonaglycol; PEG4 diamine; 3,6,9,12,15-Pentaoxaheptadecan-1-amine; Amino-PEG4-amine; Jeffamine® XTJ-511 (related polyether amine series)
EINECS	226-842-8

Quality Control

Our 2,5,8,11,14-Pentaoxahexadecan-16-Amine is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including assay by titration or HPLC and identification by FT-IR and NMR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Primary Amine Value	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.