Description

(+/-)-3-Hydroxy-γ-Butyrolactone CAS NO 5469-16-9 is a versatile chiral building block and intermediate in organic synthesis. This compound is valued for its bifunctional lactone and hydroxyl group, which enables its use in constructing complex molecular architectures. It is particularly sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of various active pharmaceutical ingredients (APIs), including potential CNS drugs and antiviral agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its stereochemistry for enhanced biological activity.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other high-value specialty chemicals.
• Polymer Chemistry: Acts as a monomer or co-monomer for creating biodegradable polymers and resins with specific functional properties.
• Asymmetric Catalysis Research: Employed as a standard substrate or ligand precursor in the development of new chiral catalysts.
• Biochemical Research: Utilized in studies related to GABA (γ-aminobutyric acid) analogues and metabolic pathway investigations.

Basic Information

Product Name	(+/-)-3-Hydroxy-γ-Butyrolactone
CAS No.	5469-16-9
Molecular Formula	C₄H₆O₃
Molecular Weight	102.09 g/mol
Synonyms	3-Hydroxybutyrolactone; DL-3-Hydroxy-γ-butyrolactone; (±)-3-Hydroxy-γ-butyrolactone; 3-Hydroxydihydro-2(3H)-furanone; 3-Hydroxy-γ-butyrolactone; rac-3-Hydroxy-γ-butyrolactone; 3-Hydroxy-γ-lactone; Tetrahydro-3-hydroxy-2-furanone
EINECS	226-764-7

Quality Control

Our (+/-)-3-Hydroxy-γ-Butyrolactone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The product is moisture-sensitive; ensure containers are kept tightly sealed to prevent absorption of water vapor.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	Racemic mixture (50:50)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.