Description

2-Phenyl-2-Ethylbutyric Acid is a versatile organic acid building block characterized by its unique phenyl and ethyl substituents on the alpha carbon. This structure makes it a valuable intermediate for synthesizing complex molecules, particularly in the pharmaceutical and agrochemical sectors, where it contributes to the development of active ingredients with specific steric and electronic properties. It is essential for research chemists and production facilities engaged in the development of fine chemicals, liquid crystal materials, and advanced polymer modifiers.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of non-steroidal anti-inflammatory drugs (NSAIDs) and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides and plant growth regulators, leveraging its aromatic moiety for biological activity.
• Liquid Crystal Compounds: Serves as a precursor in the synthesis of liquid crystal materials for display technologies due to its rigid phenyl group and flexible alkyl chain.
• Polymer Modification: Acts as a monomer or chain modifier to introduce specific functional groups into polymers, enhancing properties like thermal stability and solubility.
• Organic Synthesis & Research: A crucial building block in academic and industrial R&D for constructing complex organic molecules, including flavors, fragrances, and specialty chemicals.
• Coordination Chemistry: Can be used to synthesize ligands for metal complexes in catalytic applications.

Basic Information

Item	Detail
Product Name	2-Phenyl-2-Ethylbutyric Acid
CAS No.	5465-28-1
Molecular Formula	C₁₂H₁₆O₂
Molecular Weight	192.26 g/mol
Synonyms	α-Ethyl-α-phenylbutyric acid; 2-Ethyl-2-phenylbutanoic acid; 2-Phenyl-2-ethylbutanoic acid; (±)-2-Ethyl-2-phenylbutyric acid; DL-2-Phenyl-2-ethylbutyric acid; NSC 163063; Butyric acid, 2-ethyl-2-phenyl-; Butanoic acid, 2-ethyl-2-phenyl-
EINECS	226-763-8

Quality Control

Our 2-Phenyl-2-Ethylbutyric Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for fine chemical synthesis. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment. We adhere to cGMP principles where applicable to ensure consistency and traceability for our global customer base.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	85 - 89 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.