Description

4-Cyanophenylacetic Acid is a versatile aromatic nitrile and acetic acid derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a reactive cyano group and a carboxylic acid moiety, makes it an indispensable intermediate for constructing complex molecular architectures. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs), kinase inhibitors, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Building block for herbicides, fungicides, and plant growth regulators, leveraging the phenylacetic acid backbone.
• Liquid Crystal & OLED Materials: Used in the production of advanced electronic display components and organic light-emitting diodes due to its rigid, conjugated structure.
• Polymer & Resin Modifier: Serves as a monomer or cross-linking agent to introduce polar cyano groups, enhancing polymer adhesion and thermal stability.
• Fine Chemical Synthesis: Intermediate for dyes, pigments, and photographic chemicals where the cyano group can be further transformed.
• Bioconjugation & Linker Chemistry: The carboxylic acid allows for coupling to biomolecules, making it useful in proteomics and diagnostic reagent development.

Basic Information

Product Name	4-Cyanophenylacetic Acid
CAS No.	5462-71-5
Molecular Formula	C9H7NO2
Molecular Weight	161.16 g/mol
Synonyms	(4-Cyanophenyl)acetic Acid; p-Cyanophenylacetic Acid; 2-(4-Cyanophenyl)acetic Acid; 4-Cyanobenzeneacetic Acid; NSC 403697; p-Cyanobenzylformic Acid; 4-Cyanophenylethanoic Acid; 4-Cyano-α-toluic Acid
EINECS	226-746-4

Quality Control

Our 4-Cyanophenylacetic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP or research-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the original container is kept sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.