Description

(1-Aminocyclohexyl)Methanol Hydrochloride is a versatile chiral building block and intermediate of significant importance in organic synthesis. Its value lies in its functionalized cyclohexane ring and protected amino alcohol group, making it a key precursor for complex molecule construction. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for applications in medicinal chemistry and the synthesis of specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Peptidomimetic Synthesis: Used to introduce constrained cyclohexyl amino acid analogs into peptide chains to enhance metabolic stability and bioavailability.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis and metal complex formation.
• Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, and plant growth regulators that require a functionalized cyclohexylamine core.
• Polymer Modification: Acts as a monomer or cross-linking agent for specialty polymers, imparting specific mechanical or chemical resistance properties.
• Academic & Research Chemistry: A valuable reagent for methodological studies in organic synthesis and for creating compound libraries for biological screening.

Basic Information

Product Name	(1-Aminocyclohexyl)Methanol Hydrochloride
CAS No.	5460-68-4
Molecular Formula	C7H16ClNO
Molecular Weight	165.66 g/mol
Synonyms	1-(Aminomethyl)cyclohexanol Hydrochloride; (1-Aminomethyl-cyclohexyl)-methanol Hydrochloride; 1-(Hydroxymethyl)cyclohexanamine Hydrochloride; trans-2-Aminomethylcyclohexanol Hydrochloride; 1-Aminocyclohexanemethanol HCl; Cyclohexanemethanol, 1-amino-, hydrochloride; Aminocyclohexylmethanol Hydrochloride
EINECS	226-724-6

Quality Control

Our (1-Aminocyclohexyl)Methanol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.