Description

3-Ethyl-3-Hydroxy-2-Phenyl-Pentanoic Acid is a specialized chiral intermediate featuring a unique combination of a phenyl group and a tertiary alcohol on a carboxylic acid backbone. This compound matters for its role as a critical building block in the synthesis of complex pharmaceutical molecules, particularly those requiring specific stereochemistry. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs) and advanced organic compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the production of non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents.
• Fine Chemical Synthesis: Used in the research and development of complex organic molecules requiring specific stereocenters.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in studies of enantioselective reactions.
• Agrochemical Development: Potential intermediate in the synthesis of advanced, targeted crop protection agents.
• Academic & Industrial R&D: Employed in medicinal chemistry programs for lead optimization and structure-activity relationship (SAR) studies.

Basic Information

Product Name	3-Ethyl-3-Hydroxy-2-Phenyl-Pentanoic Acid
CAS No.	5457-09-0
Molecular Formula	C₁₃H₁₈O₃
Molecular Weight	222.28 g/mol
Synonyms	2-Phenyl-3-ethyl-3-hydroxypentanoic acid; 3-Hydroxy-3-ethyl-2-phenylpentanoic acid; 3-Ethyl-3-hydroxy-2-phenylvaleric acid; α-Phenyl-β-ethyl-β-hydroxyvaleric acid; (±)-3-Ethyl-3-hydroxy-2-phenylpentanoic acid; DL-3-Ethyl-3-hydroxy-2-phenylpentanoic acid; 5457-09-0; Pentanoic acid, 3-ethyl-3-hydroxy-2-phenyl-
EINECS	226-704-7

Quality Control

Our 3-Ethyl-3-Hydroxy-2-Phenyl-Pentanoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.