Description

2,2,5,5-Tetramethyltetrahydrofuran-3-One is a high-purity, specialized heterocyclic ketone with a unique sterically hindered structure. This compound serves as a valuable advanced intermediate and building block in sophisticated organic synthesis, enabling the development of complex molecular architectures. It is primarily utilized by R&D and production teams in the pharmaceutical, agrochemical, and fine chemical sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing complex drug molecules, particularly those requiring rigid, sterically defined frameworks.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its tetrahydrofuranone core contributes to specific biological activity.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other specialty chemicals requiring high-purity ketone intermediates.
• Material Science Research: Employed in the development of novel polymers and organic electronic materials due to its unique structural properties.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, including asymmetric synthesis and catalysis studies.
• Ligand and Catalyst Preparation: The carbonyl and ether functionalities make it a candidate for constructing chelating ligands in metal-catalyzed reactions.

Basic Information

Product Name	2,2,5,5-Tetramethyltetrahydrofuran-3-One
CAS No.	5455-94-7
Molecular Formula	C8H14O2
Molecular Weight	142.20 g/mol
Synonyms	3-Tetrahydrofuranone, 2,2,5,5-tetramethyl-; 2,2,5,5-Tetramethyl-3-oxotetrahydrofuran; 2,2,5,5-Tetramethyl-dihydro-furan-3-one; 2,2,5,5-Tetramethyloxolan-3-one; 3-Oxo-2,2,5,5-tetramethyltetrahydrofuran; Tetramethyltetrahydrofuranone
EINECS	226-704-5

Quality Control

Our 2,2,5,5-Tetramethyltetrahydrofuran-3-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and GC for residual solvents, to ensure it meets exacting specifications for use in sensitive applications. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and potential contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.