Description

3-Hydroxy-2,3-Diphenylpropionic Acid is a versatile chiral organic compound featuring both hydroxyl and carboxylic acid functional groups on a diphenylpropane backbone. This unique structure makes it a valuable intermediate for synthesizing complex molecules, particularly in the pharmaceutical sector where chirality and purity are paramount. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for applications in asymmetric synthesis and drug development.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where its structural motif contributes to biological activity.
• Fine Chemical Production: Serves as a precursor for various specialty chemicals, including liquid crystals, dyes, and perfumes.
• Asymmetric Catalysis Research: Employed as a ligand or a substrate in academic and industrial research focused on developing new chiral catalysts and synthetic methodologies.
• Polymer Modification: Can be utilized to introduce specific functional groups into polymer chains, altering their physical or chemical properties.

Basic Information

Product Name	3-Hydroxy-2,3-Diphenylpropionic Acid
CAS No.	5449-26-3
Molecular Formula	C15H14O3
Molecular Weight	242.27 g/mol
Synonyms	2,3-Diphenyl-3-hydroxypropionic Acid; α-Hydroxydiphenylacetic Acid β-Lactone (tautomer); 3-Hydroxy-2,3-diphenylpropanoic Acid; DL-3-Hydroxy-2,3-diphenylpropionic Acid; (±)-3-Hydroxy-2,3-diphenylpropionic Acid; 2,3-Diphenyl-3-hydroxypropanoic Acid; β-Hydroxy-α,β-diphenylpropionic Acid
EINECS	226-663-5

Quality Control

Our 3-Hydroxy-2,3-Diphenylpropionic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.