Description

2-Hydroxy-2-(2-Methylphenyl)-2-Phenyl-Acetic Acid is a specialized organic compound belonging to the class of diphenylacetic acid derivatives. This chemical serves as a valuable chiral building block and intermediate in advanced organic synthesis, prized for its structural complexity and functional groups. It is primarily utilized by research institutions and industrial R&D departments focused on developing novel pharmaceuticals, agrochemicals, and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting the central nervous system.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its diphenyl backbone.
• Ligand Synthesis: Acts as a starting material for creating chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the manufacture of specialty dyes, pigments, and performance chemicals requiring specific stereochemistry.
• Academic & Industrial R&D: A crucial compound for methodological studies in organic chemistry, including new reaction pathway development and stereoselective synthesis.

Basic Information

Product Name	2-Hydroxy-2-(2-Methylphenyl)-2-Phenyl-Acetic Acid
CAS No.	5448-09-9
Molecular Formula	C₁₆H₁₆O₃
Molecular Weight	256.30 g/mol
Synonyms	2-(2-Methylbenzoyl)benzoic acid; α-Hydroxy-o-tolylphenylacetic acid; 2-Hydroxy-2-(o-tolyl)-2-phenylacetic acid; Diphenylacetic acid, 2-hydroxy-2-(2-methylphenyl)-; (2-Hydroxy-2-phenyl-2-o-tolyl)acetic acid; Benzoic acid, 2-(2-methylbenzoyl)-; NSC 163022
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-2-(2-Methylphenyl)-2-Phenyl-Acetic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data (HPLC, GC, NMR, IR) upon request, supporting compliance with cGMP and ISO 9001 standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.