Description

5-o-Carbomethoxy-1,2-o-Isopropylidene-D-Xylofuranose is a high-purity, protected carbohydrate derivative, specifically a key chiral synthon and building block in organic synthesis. Its primary value lies in its role as a versatile intermediate for the production of nucleoside analogs, antiviral agents, and other complex bioactive molecules. This compound is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers focused on sugar chemistry, antiviral drug development, and advanced organic synthesis.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of nucleoside analogs and antiviral drugs.
• Organic Synthesis: Used as a protected sugar derivative to introduce specific stereochemistry and functional groups into complex molecules.
• Research & Development: Serves as a key starting material in academic and industrial R&D for exploring new therapeutic candidates and synthetic pathways.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value specialty chemicals and active pharmaceutical ingredients (APIs).
• Glycochemistry: A valuable tool in the study and synthesis of carbohydrates and glycoconjugates.

Basic Information

Item	Details
Product Name	5-o-Carbomethoxy-1,2-o-Isopropylidene-D-Xylofuranose
CAS No.	5432-33-7
Molecular Formula	C10H16O6
Molecular Weight	232.23 g/mol
Synonyms	1,2-O-Isopropylidene-5-O-(methoxycarbonyl)-D-xylofuranose; Methyl 2,3-O-Isopropylidene-β-D-ribofuranoside-5-carboxylate; 5-O-Methoxycarbonyl-1,2-O-isopropylidene-α-D-xylofuranose; D-Xylofuranose, 5-O-(methoxycarbonyl)-1,2-O-(1-methylethylidene)-; Isopropylidene-D-xylofuranose carbomethoxy derivative
EINECS	226-596-5

Quality Control

Our 5-o-Carbomethoxy-1,2-o-Isopropylidene-D-Xylofuranose is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and optical rotation measurement, to ensure high chemical purity, correct stereochemistry, and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	-30° to -35° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.