Description

1-(4-Methylphenyl)Sulfonyl-3-(Trimethylsilylcarbamoyl)Urea is a specialized organosilicon-substituted urea derivative with a sulfonyl linkage, identified by CAS NO 5408-24-2. This compound is valued for its role as a key synthetic intermediate and protecting group reagent in advanced organic synthesis. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly those requiring silyl-protected functional groups.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators where the sulfonylurea moiety is active.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing the trimethylsilylcarbamoyl group, facilitating complex molecule construction.
• Material Science Precursor: Employed in the research of specialty polymers and advanced materials with tailored surface properties.
• Chemical Biology Probe: Utilized in biochemical research to study enzyme inhibition and protein interactions involving urea-based structures.
• Process Chemistry: Applied in scalable synthetic routes for the production of high-value fine chemicals under controlled conditions.

Basic Information

Product Name	1-(4-Methylphenyl)Sulfonyl-3-(Trimethylsilylcarbamoyl)Urea
CAS No.	5408-24-2
Molecular Formula	C12H19N3O4SSi
Molecular Weight	329.45 g/mol
Synonyms	N-[(Trimethylsilyl)carbamoyl]-N'-(4-methylphenyl)sulfonylurea; Urea, N-[(trimethylsilyl)carbamoyl]-N'-(4-methylphenyl)sulfonyl-; 1-(p-Tolylsulfonyl)-3-(trimethylsilylcarbamoyl)urea; Tolylsulfonyltrimethylsilylcarbamoylurea; TS-TMSC-Urea; 5408-24-2; NSC 163047
EINECS	Contact for details

Quality Control

Our 1-(4-Methylphenyl)Sulfonyl-3-(Trimethylsilylcarbamoyl)Urea is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.