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3-(Dimethylamino)Propyl Chloride Hydrochloride CAS NO 5407-04-5


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CAS No.:5407-04-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-(Dimethylamino)Propyl Chloride Hydrochloride is a versatile organic salt widely used as a key building block in pharmaceutical synthesis and fine chemical manufacturing. This compound is valued for its role as an alkylating agent and intermediate, enabling the introduction of the 3-(dimethylamino)propyl functional group into target molecules. It is essential for researchers and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries developing active ingredients and advanced materials.

Application

  • Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the production of anticholinergic, antihistaminic, and local anesthetic drugs.
  • Agrochemical Synthesis: Used in the manufacturing of herbicides, fungicides, and plant growth regulators where the dimethylaminopropyl moiety is required.
  • Quaternary Ammonium Compound Production: Serves as a precursor for the synthesis of various quaternary ammonium salts used as surfactants, phase-transfer catalysts, and biocides.
  • Polymer Chemistry: Employed as a monomer or modifying agent in the production of specialty polymers, including ion-exchange resins and flocculants.
  • Organic Synthesis Reagent: Utilized as an alkylating agent in nucleophilic substitution reactions to introduce aminopropyl chains into complex organic molecules.
  • Bioconjugation and Linker Chemistry: Applied in the development of chemical linkers for drug-antibody conjugates (ADCs) and other bioconjugation strategies.

Basic Information

Product Name 3-(Dimethylamino)Propyl Chloride Hydrochloride
CAS No. 5407-04-5
Molecular Formula C5H13Cl2N
Molecular Weight 158.07 g/mol
Synonyms 1-Chloro-3-(dimethylamino)propane Hydrochloride; 3-Chloro-N,N-dimethylpropan-1-amine Hydrochloride; (3-Chloropropyl)dimethylamine Hydrochloride; N,N-Dimethyl-3-chloropropylamine Hydrochloride; DMAP-HCl; 3-Dimethylaminopropyl Chloride Hydrochloride; γ-Dimethylaminopropyl Chloride Hydrochloride; N,N-Dimethyl-3-aminopropyl Chloride Hydrochloride
EINECS 226-500-6

Quality Control

Our 3-(Dimethylamino)Propyl Chloride Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) documenting purity, identity, and impurity profiles are provided with every shipment to ensure traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Melting Point 168°C - 172°C
Loss on Drying ≤ 1.0%
Heavy Metals (as Pb) ≤ 20 ppm
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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