Description

2-Methyl-5,6-Dihydro-4H-Pyran-3-Carboxylic Acid is a versatile heterocyclic building block and fine chemical intermediate of significant importance in advanced organic synthesis. Its unique dihydropyran structure functionalized with a carboxylic acid group makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for molecules containing dihydropyran or tetrahydropyran motifs.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators where its heterocyclic core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, including flavors, fragrances, and advanced polymers.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry, including cycloaddition reactions and ring-opening polymerizations.
• Material Science: Potential building block for novel monomers or additives in polymer chemistry to impart specific properties.

Basic Information

Product Name	2-Methyl-5,6-Dihydro-4H-Pyran-3-Carboxylic Acid
CAS No.	5399-21-3
Molecular Formula	C7H10O3
Molecular Weight	142.15 g/mol
Synonyms	3-Carboxy-2-methyl-5,6-dihydro-4H-pyran; 2-Methyl-4,5-dihydro-3-furancarboxylic acid (tautomer); 2-Methyl-δ3-dihydro-4H-pyran-3-carboxylic acid; 5,6-Dihydro-2-methyl-4H-pyran-3-carboxylic acid; 2-Methyl-3-carboxy-5,6-dihydropyran; Dihydro-2-methyl-4H-pyran-3-carboxylic acid
EINECS	226-402-6

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our standard grade for 2-Methyl-5,6-Dihydro-4H-Pyran-3-Carboxylic Acid typically meets a purity specification of ≥95% (by HPLC), with options for higher grades (≥98%, ≥99%) available to suit specific project requirements. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, and we support our clients' needs for regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials such as strong oxidizing agents, strong bases, and strong reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.