Description

4-tert-Butylanisole is a versatile aromatic ether compound, valued for its role as a key intermediate and building block in advanced organic synthesis. Its chemical structure, featuring a tert-butyl group and a methoxybenzene core, makes it particularly useful for introducing steric bulk and modifying solubility profiles in target molecules. This product is essential for R&D and production in the pharmaceutical, agrochemical, and specialty fragrance industries.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly where the tert-butyl-anisole moiety is required for specific biological activity or metabolic stability.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of herbicides, fungicides, and plant growth regulators, leveraging its aromatic backbone for effective crop protection chemicals.
• Fragrance and Flavor Ingredient: Acts as a starting material or modifier in the production of synthetic musks and other complex aroma chemicals due to its stable, substituted anisole structure.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and etherification processes to create more complex, functionalized organic compounds for material science.
• Liquid Crystal and Polymer Additive: Utilized in research for developing specialty polymers and liquid crystal displays (LCDs) where its molecular geometry can influence material properties.

Basic Information

Product Name	4-tert-Butylanisole
CAS No.	5396-38-3
Molecular Formula	C11H16O
Molecular Weight	164.24 g/mol
Synonyms	1-tert-Butyl-4-methoxybenzene; p-tert-Butylanisole; 4-(tert-Butyl)anisole; Anisole, 4-(1,1-dimethylethyl)-; 4-tert-Butylmethoxybenzene; p-(tert-Butyl)phenyl methyl ether; 1-Methoxy-4-tert-butylbenzene; Butylated Hydroxyanisole (BHA) related intermediate
EINECS	226-394-5

Quality Control

Our 4-tert-Butylanisole is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing including GC, HPLC, and NMR to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing specific results for purity, water content, and related substances is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Refractive Index (20°C)	1.505 - 1.515
Density (20°C)	0.940 - 0.960 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.