Description

2-Hydroxytetrahydrofuran is a versatile heterocyclic building block and chiral intermediate of significant importance in fine chemical synthesis. Its bifunctional structure, containing both a hydroxyl group and a tetrahydrofuran ring, makes it a valuable precursor for pharmaceuticals, agrochemicals, and specialty materials. This compound is particularly sought after by R&D and production teams in the pharmaceutical and advanced chemical manufacturing sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral and cardiovascular drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Polymer & Resin Modifier: Serves as a monomer or cross-linking agent for specialty polymers, enhancing flexibility and adhesion properties.
• Solvent & Reaction Medium: Employed as a polar aprotic solvent in sensitive organic transformations and Grignard reactions.
• Ligand & Catalyst Preparation: Utilized in the synthesis of chiral ligands for asymmetric catalysis and metal complexes.
• Flavor & Fragrance Industry: Acts as a building block for synthetic aroma chemicals and flavorants.

Basic Information

Product Name	2-Hydroxytetrahydrofuran
CAS No.	5371-52-8
Molecular Formula	C4H8O2
Molecular Weight	88.11 g/mol
Synonyms	2-Tetrahydrofuranol; Tetrahydro-2-furanol; 2-Hydroxyoxolane; 2-THF-OH; α-Hydroxytetrahydrofuran; 2-Oxolanol; Butane-1,4-diol cyclic ether, 2-hydroxy-; 2-Furanol, tetrahydro-
EINECS	226-348-1

Quality Control

Our 2-Hydroxytetrahydrofuran is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources, open flames, and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed when not in use to minimize moisture absorption and oxidation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Rotation (if chiral)	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.