Description

Tetrahydropyran-4,4-Dicarboxylic Acid CAS NO 5337-04-2 is a versatile bifunctional organic compound featuring a saturated tetrahydropyran ring core with two carboxylic acid groups. This structure makes it a valuable building block for synthesizing complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by research chemists and process development scientists for creating active pharmaceutical ingredients (APIs), ligands, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, including protease inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging its rigid cyclic structure.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Acts as a monomer or cross-linking agent for producing specialty polyesters and polyamides with unique thermal properties.
• Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and material science applications.
• Fine Chemical Production: Integral to the synthesis of complex flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	Tetrahydropyran-4,4-Dicarboxylic Acid
CAS No.	5337-04-2
Molecular Formula	C8H12O5
Molecular Weight	188.18 g/mol
Synonyms	4,4-Bis(carboxymethyl)tetrahydropyran; 4,4-Dicarboxymethyltetrahydropyran; Tetrahydropyran-4,4-diacetic acid; 4-Oxane-4,4-diyldiacetic acid; THP-4,4-dicarboxylic acid; 1,1'-(Tetrahydro-2H-pyran-4,4-diyl)diacetic acid; 4,4-Pyrandicarboxylic acid
EINECS	226-257-5

Quality Control

Our Tetrahydropyran-4,4-Dicarboxylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration, to ensure high purity and batch-to-batch consistency suitable for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.