Description

Tetrahydro-4-Oxo-2H-Pyran-2-Carboxylic Acid is a versatile lactone-based carboxylic acid derivative that serves as a critical chiral building block and synthetic intermediate. Its unique fused ring structure makes it valuable for constructing complex molecular architectures with high stereochemical control. This compound is primarily sought after by research and development chemists in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Catalysis: Used as a precursor for ligands and catalysts in enantioselective synthesis.
• Fine Chemical Production: Building block for specialty chemicals, agrochemicals, and advanced materials.
• Academic & Industrial Research: Valuable reagent for methodological development in organic chemistry and total synthesis projects.
• Flavor & Fragrance Industry: Potential intermediate for the synthesis of complex lactone-based aroma compounds.

Basic Information

Product Name	Tetrahydro-4-Oxo-2H-Pyran-2-Carboxylic Acid
CAS No.	5270-59-7
Molecular Formula	C6H8O4
Molecular Weight	144.13 g/mol
Synonyms	4-Oxotetrahydro-2H-pyran-2-carboxylic acid; 2-Carboxy-4-oxotetrahydropyran; 4-Oxo-tetrahydro-pyran-2-carboxylic acid; 2H-Pyran-2-carboxylic acid, tetrahydro-4-oxo-; Tetrahydro-4-oxo-2H-pyran-2-carboxylic acid; 4-Oxo-tetrahydropyran-2-carboxylic acid; Dihydro-5-oxo-2-furancarboxylic acid (tautomeric form); 5-Oxo-dihydro-furan-2-carboxylic acid
EINECS	226-086-4

Quality Control

Our Tetrahydro-4-Oxo-2H-Pyran-2-Carboxylic Acid is manufactured under a strict quality management system. Each batch is analyzed to ensure it meets high-purity standards suitable for research and synthetic applications. Standard quality control includes identity confirmation by spectroscopic methods (IR, NMR) and purity assessment by chromatographic techniques (HPLC). A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to minimize exposure to moisture and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.