Description

2,2-Dimethyl-4-Cyanotetrahydropyran-4-Ol is a versatile heterocyclic building block characterized by its cyano and hydroxyl functional groups on a tetrahydropyran scaffold. This compound matters as a critical chiral intermediate in the synthesis of complex pharmaceuticals and advanced organic materials. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its structural complexity for biological activity.
• Fine Chemical Production: Serves as a versatile building block for synthesizing specialty chemicals, flavors, and fragrances.
• Academic & Industrial Research: A valuable reagent in methodological chemistry research, including asymmetric synthesis and catalysis studies.
• Material Science Precursor: Potential use in the development of novel polymers or functional materials due to its reactive functional groups.

Basic Information

Product Name	2,2-Dimethyl-4-Cyanotetrahydropyran-4-Ol
CAS No.	5270-55-3
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	4-Cyano-2,2-dimethyltetrahydro-2H-pyran-4-ol; 2,2-Dimethyl-4-cyano-4-hydroxytetrahydropyran; 4-Hydroxy-2,2-dimethyltetrahydro-2H-pyran-4-carbonitrile; 4-Cyano-4-hydroxy-2,2-dimethyltetrahydropyran; 2,2-Dimethyltetrahydro-2H-pyran-4-carbonitrile, 4-ol; 5270-55-3 (CAS Name); THP-protected cyanohydrin derivative.
EINECS	Contact for details

Quality Control

Our 2,2-Dimethyl-4-Cyanotetrahydropyran-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.