Description

3'-Hydroxy-3,5,6,7,8,4',5'-Heptamethoxyflavone is a highly substituted polymethoxyflavone (PMF), a significant subclass of flavonoid compounds known for their potent biological activities. This specific heptamethoxyflavone derivative is valued for its role as a key reference standard and active pharmaceutical ingredient (API) intermediate in advanced research and development. It is primarily utilized by research institutions and pharmaceutical companies focused on nutraceuticals, oncology, and metabolic disease therapeutics.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of flavonoid content in drug substances and herbal extracts via HPLC, LC-MS, and NMR.
• Nutraceutical & Dietary Supplement Research: Serves as a critical compound in studying the bioavailability, metabolism, and health benefits of citrus-derived polymethoxyflavones.
• Oncology & Anti-cancer Drug Discovery: Investigated for its potential anti-proliferative, pro-apoptotic, and anti-angiogenic properties in various cancer cell lines.
• Anti-inflammatory & Neuroprotective Agent Development: Employed in preclinical research targeting inflammatory pathways and neurodegenerative conditions.
• Metabolic Syndrome Research: Studied for its effects on lipid metabolism, insulin sensitivity, and obesity-related parameters.
• Cosmeceutical Ingredient: Evaluated for antioxidant and skin-protective benefits in advanced cosmetic formulations.
• Biochemical & Pharmacological Screening: Acts as a lead compound or positive control in high-throughput screening assays.
• Academic & Institutional Research: Used in universities and labs for fundamental studies on flavonoid chemistry and bioactivity.

Basic Information

Product Name	3'-Hydroxy-3,5,6,7,8,4',5'-Heptamethoxyflavone
CAS No.	5244-28-0
Molecular Formula	C₂₂H₂₄O₁₁
Molecular Weight	464.42 g/mol
Synonyms	3'-Hydroxy-3,5,6,7,8,4',5'-heptamethoxyflavone; 3',5-Dihydroxy-3,4',5',6,7,8-hexamethoxyflavone; 5-Hydroxy-3,6,7,8,3',4',5'-heptamethoxyflavone; Heptamethoxyflavone; HMF; NSC 407303; Flavone, 3'-hydroxy-3,5,6,7,8,4',5'-heptamethoxy-
EINECS	Contact for details

Quality Control

Our 3'-Hydroxy-3,5,6,7,8,4',5'-Heptamethoxyflavone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool environment. This compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive); prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥95.0% (Area %)
Purity (Titration)	Contact for details
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.