Description

Axillarin is a high-purity flavonoid compound, also known as 3,5,7,4'-tetrahydroxy-3'-methoxyflavone, valued for its role as a key phytochemical reference standard and research intermediate. Its significance lies in providing researchers and manufacturers with a reliable, well-characterized compound for analytical method development, biological activity studies, and quality control of botanical extracts. This product is essential for professionals in the pharmaceutical, nutraceutical, and academic research sectors who require consistent, high-quality materials for their development and analytical workflows.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and impurity profiling of flavonoid-containing drugs and herbal medicinal products.
• Nutraceutical & Dietary Supplement Analysis: Serves as a quantitative standard in HPLC and LC-MS methods to ensure the potency and authenticity of botanical extracts like those from Artemisia species.
• Biochemical & Pharmacological Research: Employed in in vitro and in vivo studies to investigate potential anti-inflammatory, antioxidant, and neuroprotective activities.
• Academic & Institutional Research: A critical tool for universities and research institutes studying flavonoid biosynthesis, metabolism, and structure-activity relationships.
• Cosmeceutical Ingredient Research: Investigated for its potential application in skincare formulations due to its antioxidant properties.
• Food & Beverage Science: Used in research focused on the bioactive flavonoid content of foods and beverages for nutritional labeling and health claim substantiation.

Basic Information

Product Name	Axillarin
CAS No.	5188-73-8
Molecular Formula	C₁₆H₁₂O₇
Molecular Weight	316.26 g/mol
Synonyms	3,5,7,4'-Tetrahydroxy-3'-methoxyflavone; 3'-Methoxyquercetin; 3'-O-Methylquercetin; 4',5,7-Trihydroxy-3'-methoxyflavonol; Quercetin 3'-methyl ether; Axillarin; 5,7,4'-Trihydroxy-3'-methoxyflavonol; Kumatakenin (Note: Often used interchangeably, though some sources differentiate).
EINECS	Contact for details

Quality Control

Our Axillarin is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (UV, IR, NMR) for structural confirmation, to ensure it meets the high standards required for research and analytical applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting the specific results for that lot.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.