Description

Methylzinc Chloride is an organozinc reagent with the CAS number 5158-46-3, serving as a versatile methylating agent and a key precursor in organometallic synthesis. Its primary value lies in facilitating efficient carbon-carbon bond formation and introducing methyl groups in complex molecular architectures under controlled conditions. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors, where precise synthetic methodology is critical.

Application

• Pharmaceutical Intermediate Synthesis: Used as a methyl transfer reagent in the production of active pharmaceutical ingredients (APIs) and complex organic molecules.
• Agrochemical Manufacturing: Employed in the synthesis of pesticides, herbicides, and plant growth regulators requiring specific methyl-group substitutions.
• Polymer & Material Science: Acts as a catalyst or co-catalyst in Ziegler-Natta type polymerizations and the development of novel organometallic frameworks.
• Organic Synthesis & Research: A fundamental reagent for Negishi cross-coupling reactions, enabling the formation of new carbon-carbon bonds in academic and industrial R&D settings.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, flavors, and fragrances where selective methylation is required.
• Semiconductor Precursor: Investigated for use in Metal-Organic Chemical Vapor Deposition (MOCVD) processes for thin-film and semiconductor material growth.

Basic Information

Product Name	Methylzinc Chloride
CAS No.	5158-46-3
Molecular Formula	CH3ClZn
Molecular Weight	115.84 g/mol
Synonyms	Chloromethylzinc; Zinc, chloromethyl-; Methyl zinc chloride; Methylzinc chloride solution; Chloro(methyl)zinc; Methylzincchloride; (Chloromethyl)zinc; Methyl zincchloride
EINECS	225-941-0

Quality Control

Our Methylzinc Chloride is produced and handled under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including assay by titration and impurity profile analysis, to ensure consistency and high purity suitable for synthetic applications. Certificates of Analysis (COA) documenting identity, purity, and safety parameters are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly reactive and moisture-sensitive nature, this material must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for extended stability. Keep away from heat, sparks, open flames, and incompatible materials such as strong acids, oxidizers, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (IR)	Conforms
Assay (as CH3ClZn)	≥ 95.0%
Concentration (in solvent)	Typically 1.0 M in Diethyl Ether or THF
Zinc Content	Contact for details
Impurities (by GC/MS)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.