Description

Aloin CAS NO 5133-19-7 is a bioactive anthrone C-glycoside, a primary active constituent derived from the Aloe vera plant. This compound is valued for its significant biological properties, including potent laxative effects and notable antioxidant activity. It serves as a critical intermediate and reference standard for research and development in the pharmaceutical, nutraceutical, and cosmetic industries, where purity and consistency are paramount.

Application

• Pharmaceutical Intermediates: Used as a key starting material or active pharmaceutical ingredient (API) in the formulation of laxative and digestive health products.
• Analytical Reference Standards: Serves as a high-purity certified reference material (CRM) for quality control and method validation in HPLC and other analytical techniques.
• Nutraceutical & Dietary Supplements: Incorporated into herbal and botanical supplement formulations for its purported therapeutic benefits.
• Cosmetic & Skincare Research: Investigated for its antioxidant and potential skin-conditioning properties in advanced cosmetic formulations.
• Biochemical & Pharmacological Research: Utilized in academic and industrial laboratories to study mechanisms of action, bioavailability, and metabolic pathways.
• Quality Control & Standardization: Essential for standardizing Aloe vera extracts, ensuring batch-to-batch consistency and potency in finished products.

Basic Information

Product Name	Aloin
CAS No.	5133-19-7
Molecular Formula	C21H22O9
Molecular Weight	418.39 g/mol
Synonyms	Barbaloin; Aloe-emodin anthrone C-glucoside; 10-Glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone; Aloin A; 1,8-Dihydroxy-3-(hydroxymethyl)-10-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]anthracen-9-one; Socaloin (mixture with isobarbaloin); Rhabarberone
EINECS	225-881-1

Quality Control

Our Aloin is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including HPLC for assay and related substance profiling, to meet stringent specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, supporting compliance in GMP, pharmaceutical, and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to pale brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.