Description

6-Chloropyridazine-3-Carboxylic Acid is a versatile heterocyclic building block of significant importance in modern synthetic chemistry. Its core value lies in its bifunctional structure, featuring both a reactive carboxylic acid group and a halogenated pyridazine ring, enabling its use as a key intermediate for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing the pyridazine pharmacophore.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the chloropyridazine moiety can impart specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the development of advanced organic materials, such as polymers with specific electronic properties or metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to R&D and pilot-scale production.
• Academic and Industrial R&D: Utilized in discovery chemistry for creating compound libraries and exploring new chemical spaces in medicinal and synthetic chemistry programs.

Basic Information

Item	Details
Product Name	6-Chloropyridazine-3-Carboxylic Acid
CAS No.	5096-73-1
Molecular Formula	C5H3ClN2O2
Molecular Weight	158.54 g/mol
Synonyms	3-Chloro-6-pyridazinecarboxylic Acid; 6-Chloro-3-pyridazinecarboxylic Acid; 6-Chloropyridazine-3-carboxylic acid; 3-Carboxy-6-chloropyridazine; 6-Chloro-pyridazine-3-carboxylic acid; 6-Chloro-3-carboxypyridazine; 6-Chloro-3-pyridazinylcarboxylic Acid
EINECS	Contact for details

Quality Control

Every batch of 6-Chloropyridazine-3-Carboxylic Acid is produced and tested under a strict quality management system to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC chromatograms and NMR spectra, to verify identity and purity. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting key parameters such as assay, impurity profile, and residual solvents. Our quality commitment supports applications requiring material of research and development grade through to GMP-standard intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed when not in use to prevent moisture absorption. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.