Description

5-Hydroxy-2-(3-Hydroxy-4,5-Dimethoxyphenyl)-3,6,7,8-Tetramethoxy-4H-1-Benzopyran-4-One is a high-purity, multi-functional flavonoid derivative with significant biological activity. This compound is valued for its role as a key intermediate in advanced pharmaceutical research and synthesis. It is primarily sought by research institutions and manufacturers in the pharmaceutical, nutraceutical, and fine chemical sectors for developing novel therapeutic agents and reference standards.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Biochemical Research: Used as a reference standard and active probe in studies of enzyme inhibition, antioxidant pathways, and cellular signaling.
• Natural Product Synthesis: Serves as a key precursor in the semi-synthesis or total synthesis of complex natural flavonoids and their analogs.
• Nutraceutical Development: Investigated for incorporation into advanced dietary supplements targeting oxidative stress and metabolic health.
• Cosmeceutical Applications: Explored for use in high-end skincare formulations for its potential antioxidant and protective properties.
• Analytical Standard: Employed as a high-purity certified reference material (CRM) for quality control and method validation in analytical laboratories.

Basic Information

Product Name	5-Hydroxy-2-(3-Hydroxy-4,5-Dimethoxyphenyl)-3,6,7,8-Tetramethoxy-4H-1-Benzopyran-4-One
CAS No.	5065-10-1
Molecular Formula	C21H22O10
Molecular Weight	434.39 g/mol
Synonyms	5-Hydroxy-2-(3-hydroxy-4,5-dimethoxyphenyl)-3,6,7,8-tetramethoxy-4H-chromen-4-one; 3,5,6,7,8-Pentamethoxy-2-(3-hydroxy-4,5-dimethoxyphenyl)-4H-1-benzopyran-4-one; 5-Hydroxy-3,6,7,8,3',4'-hexamethoxyflavone; Hexamethoxyflavone; HMF; Artemetin (common name for this flavonoid); NSC 407347; Flavone, 5-hydroxy-3,6,7,8,3',4'-hexamethoxy-
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-2-(3-Hydroxy-4,5-Dimethoxyphenyl)-3,6,7,8-Tetramethoxy-4H-1-Benzopyran-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure compliance with research and pharmaceutical-grade standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.