Description

2-Cyclohexyl-1,1,3,3-tetramethylguanidine is a sterically hindered, strong organic base widely used as a non-nucleophilic catalyst and reagent. Its high basicity and low nucleophilicity make it exceptionally valuable for promoting reactions where traditional bases may cause unwanted side reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries, particularly for deprotonation, condensation, and polymerization processes.

Application

• Pharmaceutical Synthesis: As a catalyst for the production of active pharmaceutical ingredients (APIs), particularly in base-sensitive reactions and the synthesis of heterocyclic compounds.
• Polymer Chemistry: A key catalyst in the production of polyurethanes, polycarbonates, and other specialty polymers, where it controls reaction rates and polymer chain length.
• Agrochemical Manufacturing: Used in the synthesis of advanced pesticides and herbicides, facilitating efficient condensation and cyclization steps.
• Organic Synthesis Reagent: Employed as a strong, non-nucleophilic base for deprotonation, enolate formation, and the synthesis of fine chemicals and complex organic molecules.
• Chemical Research & Development: A versatile tool in R&D labs for exploring new reaction pathways and optimizing synthetic methodologies.

Basic Information

Product Name	2-Cyclohexyl-1,1,3,3-Tetramethylguanidine
CAS No.	5012-76-0
Molecular Formula	C11H23N3
Molecular Weight	197.32 g/mol
Synonyms	Cyclohexyltetramethylguanidine; 1-Cyclohexyl-2,2,4,4-tetramethylguanidine; Tetramethylcyclohexylguanidine; TMCG; CTMG; Guanidine, N-cyclohexyl-N',N',N'',N''-tetramethyl-; N-Cyclohexyl-N',N',N'',N''-tetramethylguanidine
EINECS	225-700-9

Quality Control

Our 2-Cyclohexyl-1,1,3,3-tetramethylguanidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including assay, purity profiling, and identity confirmation, to ensure it meets the high standards required for industrial and research applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its strong basic nature, store separately from acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.480 - 1.490
Density (20°C)	0.92 - 0.96 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.