Description

2-Chloro-2-Methylpropionic Acid is a versatile chlorinated carboxylic acid derivative, also known as trimethylacetic acid chloride. This compound serves as a crucial building block and intermediate in advanced organic synthesis, valued for its reactivity and the steric bulk of the neopentyl-like structure it imparts. It is primarily utilized by pharmaceutical, agrochemical, and specialty polymer manufacturers for the production of active ingredients, functional monomers, and performance chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing the pivaloyl (trimethylacetyl) group.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and plant growth regulators where its chlorinated structure provides specific biological activity.
• Polymer & Resin Modifier: Acts as a functional monomer or chain transfer agent in the production of specialty acrylic resins, coatings, and adhesives to modify properties.
• Organic Synthesis Reagent: Employed in esterification and acylation reactions to create esters, amides, and acid chlorides for further chemical transformations.
• Liquid Crystal & Electronic Materials: Serves as a precursor in the synthesis of advanced materials for display and semiconductor applications.
• Flavor & Fragrance Industry: Intermediate for the production of certain esters used in synthetic flavors and fragrances.

Basic Information

Item	Details
Product Name	2-Chloro-2-Methylpropionic Acid
CAS No.	594-58-1
Molecular Formula	C4H7ClO2
Molecular Weight	122.55 g/mol
Synonyms	Trimethylacetyl Chloride; Pivaloyl Chloride; 2,2-Dimethylpropionyl Chloride; Neopentanoyl Chloride; Pivalic Acid Chloride; 2-Chloro-2,2-dimethylethanoic Acid; α-Chloropivalic Acid (less common); NSC 8425
EINECS	209-854-0

Quality Control

Our 2-Chloro-2-Methylpropionic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We adhere to cGMP principles where applicable to ensure consistency, traceability, and reliability for our global B2B customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases, oxidizers, and moisture. Recommended storage temperature is between 15°C and 25°C. Due to its nature as a strong acid/organic solvent, containers must be kept tightly sealed to prevent hydrolysis and reaction with atmospheric moisture.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Acidity (Titration)	Conforms
Specific Gravity (20°C)	1.00 - 1.05
Refractive Index (n20D)	1.410 - 1.420

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.