Description

4-Bromobenzyl Chloride is a versatile and high-purity organic halide building block essential for advanced chemical synthesis. Its bifunctional nature, featuring both a reactive benzyl chloride and a bromoaryl group, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in cross-coupling reactions, nucleophilic substitutions, and as a precursor to various functionalized derivatives.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the bromobenzyl moiety is incorporated into the final molecule.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts used in homogeneous catalysis.
• Material Science Monomer: Employed in the creation of functionalized polymers and advanced organic materials with specific electronic or structural properties.
• Cross-Coupling Reactions: A valuable substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Chemical Research & Development: A standard reagent in organic synthesis labs for introducing the 4-bromobenzyl group into target molecules.

Basic Information

Product Name	4-Bromobenzyl Chloride
CAS No.	589-17-3
Molecular Formula	C7H6BrCl
Molecular Weight	205.48 g/mol
Synonyms	1-(Bromomethyl)-4-chlorobenzene; α-Bromo-p-tolyl Chloride; (4-Bromophenyl)methyl Chloride; p-Bromobenzyl Chloride; 4-Bromobenzylchloride; 4-Bromophenylmethyl Chloride; NSC 406908; 589-17-3
EINECS	209-647-3

Quality Control

Our 4-Bromobenzyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment ensures the material meets the stringent requirements for research and industrial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and light-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent moisture absorption and decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	38°C - 42°C
Water Content (KF)	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.