Description

2-Bromoterephthalic Acid is a high-purity brominated aromatic dicarboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive bromine substituent and two carboxylic acid functional groups on a benzene ring, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require a versatile intermediate for creating complex molecules, such as active pharmaceutical ingredients (APIs), liquid crystal polymers, and metal-organic frameworks (MOFs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly where a bromine handle is needed for further functionalization via cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators that require brominated aromatic cores for enhanced bioactivity.
• Liquid Crystal & Polymer Chemistry: Serves as a monomer or co-monomer for producing high-performance polymers, including polyamides, polyesters, and liquid crystal polymers (LCPs) with specific thermal and mechanical properties.
• Metal-Organic Frameworks (MOFs): Acts as a versatile organic linker in the construction of porous MOF materials for gas storage, separation, and catalysis applications.
• Organic Electronic Materials: Employed in the research and development of organic semiconductors, light-emitting diodes (OLEDs), and other electronic materials due to its conjugated aromatic structure.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating novel chemical entities.
• Dye & Pigment Intermediate: Used in the synthesis of specialized dyes and pigments where bromine substitution alters color properties and lightfastness.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Sonogashira couplings, facilitating carbon-carbon bond formation.

Basic Information

Product Name	2-Bromoterephthalic Acid
CAS No.	586-35-6
Molecular Formula	C8H5BrO4
Molecular Weight	245.03 g/mol
Synonyms	2-Bromobenzene-1,4-dicarboxylic Acid; Terephthalic Acid, 2-Bromo-; 4-Bromophthalic Acid (isomer); 2-Bromo-1,4-benzenedicarboxylic Acid; 2-Bromoterephthalicacid; 4-Carboxy-3-bromobenzoic Acid; Bromoterephthalic Acid
EINECS	209-583-7

Quality Control

Our 2-Bromoterephthalic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	285 - 290 °C (dec.)
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.