Description

2-Bromobenzyl Chloride is a versatile and reactive aromatic halide building block, essential for advanced organic synthesis. Its bifunctional nature, featuring both a benzyl chloride and an aryl bromide moiety, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as active pharmaceutical ingredient (API) synthesis and ligand preparation.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring benzylated or aryl-brominated structures.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where its halogenated aromatic core is incorporated into bioactive molecules.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands for metal catalysis and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of novel polymers, liquid crystals, and organic electronic materials as a functional monomer or cross-linking agent.
• Chemical Derivatization: Useful for introducing the 2-bromobenzyl group into target molecules via nucleophilic substitution reactions, enabling further functionalization through cross-coupling (e.g., Suzuki, Heck reactions).

Basic Information

Product Name	2-Bromobenzyl Chloride
CAS No.	578-51-8
Molecular Formula	C7H6BrCl
Molecular Weight	205.48 g/mol
Synonyms	1-(Bromomethyl)-2-chlorobenzene; α-Bromo-o-chlorotoluene; 2-Chlorobenzyl Bromide; o-Bromobenzyl Chloride; (2-Bromophenyl)methyl Chloride; 2-Chloro-α-bromotoluene; NSC 406908; 1-Chloro-2-(bromomethyl)benzene
EINECS	209-425-4

Quality Control

Our 2-Bromobenzyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming key parameters such as assay and impurity profiles. We adhere to relevant industry guidelines to ensure product consistency and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.