Description

Flavanomarein is a bioactive flavonoid compound, a key marker constituent found in plants such as *Citrus aurantium* L. (bitter orange). This high-purity standard is essential for research and development, providing a reliable reference for analytical and pharmacological studies. It is primarily utilized by the pharmaceutical, nutraceutical, and analytical chemistry industries for quality control, method validation, and as a precursor in the synthesis of more complex bioactive molecules.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and purity testing of herbal extracts and finished products.
• Nutraceutical & Dietary Supplement Analysis: Serves as a quantitative marker in the quality control of bitter orange (*Citrus aurantium*) extracts and related supplements.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate potential biological activities, including antioxidant, anti-inflammatory, and metabolic effects.
• Analytical Method Development: Critical for developing and validating HPLC, LC-MS, and other chromatographic methods in analytical laboratories.
• Cosmeceutical Ingredient Research: Investigated for potential skin-beneficial properties in advanced cosmetic formulations.
• Food & Beverage Science: Used in the analysis of flavonoid content in citrus-based foods and beverages for authenticity and quality assessment.

Basic Information

Product Name	Flavanomarein
CAS No.	577-38-8
Molecular Formula	C27H32O14
Molecular Weight	580.54 g/mol
Synonyms	Flavanomarein; 5,6,7,3',4'-Pentahydroxyflavanone-7-rutinoside; Hesperetin 7-O-rutinoside; Isosakuranetin 7-O-rutinoside; 2,3-Dihydro-5,6,7,3',4'-pentahydroxyflavone 7-rutinoside; (2S)-5,6,7,3',4'-Pentahydroxyflavanone 7-rutinoside; Naringenin 7-O-rutinoside (common misidentification)
EINECS	Contact for details

Quality Control

Our Flavanomarein is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. The product is suitable for use as an analytical standard in compliance with current Good Manufacturing Practice (cGMP) principles for active pharmaceutical ingredients (APIs).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.