Description

(2R)-2α-(4-Hydroxyphenyl)-3,4-Dihydro-2H-1-Benzopyran-3α,4α,7,8-Tetrol is a high-purity, complex flavonoid derivative with a defined stereochemistry, valued for its role as a key intermediate in advanced organic synthesis and pharmaceutical research. This compound is essential for developing novel therapeutic agents and fine chemicals due to its unique polyphenolic structure and chiral centers. It is primarily sought by research institutions, pharmaceutical development labs, and specialty chemical manufacturers focused on creating bioactive molecules, natural product analogs, and high-value chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block for the synthesis of novel drug candidates, particularly in cardiovascular and anti-inflammatory research.
• Biochemical Research: Used as a reference standard and probe in studies investigating flavonoid metabolism, antioxidant mechanisms, and enzyme interactions.
• Natural Product Synthesis: A key precursor for the semi-synthesis or total synthesis of complex natural products and their derivatives for biological screening.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals where high purity and specific stereochemistry are required for advanced applications.
• Cosmeceutical Actives: Potential ingredient in the development of high-end skincare formulations targeting oxidative stress and skin aging, due to its polyphenolic structure.

Basic Information

Item	Details
Product Name	(2R)-2α-(4-Hydroxyphenyl)-3,4-Dihydro-2H-1-Benzopyran-3α,4α,7,8-Tetrol
CAS No.	577-30-0
Molecular Formula	C15H14O6
Molecular Weight	290.27 g/mol
Synonyms	(2R)-2,3-trans-3,4-cis-Leucocyanidin; 2,3-trans-3,4-cis-Leucocyanidin; Leucocyanidol; (+)-Leucocyanidol; (2R,3S,4S)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,4,5,7-tetrol; 3,4-cis-Leucocyanidin; Flavanol derivative 577-30-0
EINECS	Contact for details

Quality Control

Every batch of (2R)-2α-(4-Hydroxyphenyl)-3,4-Dihydro-2H-1-Benzopyran-3α,4α,7,8-Tetrol is produced and tested under a strict quality management system. We ensure compliance with relevant standards for research and pharmaceutical intermediates. Comprehensive analytical testing, including HPLC for purity and chiral analysis, is performed. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and product integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.