Description

7-Methoxy-4-(Trifluoromethyl)Coumarin is a specialized fluorinated coumarin derivative, a key building block in advanced organic synthesis. This compound matters for its unique photophysical properties and structural motif, which are leveraged in the development of high-performance materials and active pharmaceutical ingredients. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for applications ranging from fluorescent probes to the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A crucial synthon for the development of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Fluorescent Probe Synthesis: Serves as a core structure for creating sensitive and selective fluorescent dyes and sensors used in bioimaging and diagnostic assays.
• Agrochemical Research: Used in the synthesis of new-generation pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Organic Light-Emitting Diodes (OLEDs): Acts as an electron-transport material or a host/emitter in the fabrication of efficient OLED devices due to its favorable electronic properties.
• Polymer Chemistry: Incorporated into polymer backbones to impart specific characteristics like fluorescence, stability, or reactivity for advanced functional materials.
• Chemical Biology Tool: Utilized in the design of activity-based probes (ABPs) and photoaffinity labels for studying enzyme function and protein interactions.

Basic Information

Item	Detail
Product Name	7-Methoxy-4-(Trifluoromethyl)Coumarin
CAS No.	575-04-2
Molecular Formula	C₁₁H₇F₃O₃
Molecular Weight	244.17 g/mol
Synonyms	4-(Trifluoromethyl)-7-methoxycoumarin; 7-Methoxy-4-trifluoromethylcoumarin; 7-Methoxy-4-(trifluoromethyl)-2H-chromen-2-one; 4-Trifluoromethyl-7-methoxycoumarin; 2H-1-Benzopyran-2-one, 7-methoxy-4-(trifluoromethyl)-; 7-Methoxy-4-(trifluoromethyl)-2H-1-benzopyran-2-one
EINECS	Contact for details

Quality Control

Our 7-Methoxy-4-(Trifluoromethyl)Coumarin is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure high consistency and reliability for your research and production needs. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.