Description

7-Hydroxy-4-(Trifluoromethyl)Coumarin is a versatile fluorinated coumarin derivative that serves as a critical building block and functional material. Its value lies in the unique photophysical properties imparted by the trifluoromethyl group, making it highly sought after for advanced applications. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing new fluorinated molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel fluorinated drug candidates, particularly in oncology and CNS therapeutic areas.
• Fluorescent Probe & Sensor Development: Used as a core structure for creating sensitive chemosensors and bioimaging agents due to its modifiable fluorescence.
• Agrochemical Research: Serves as a precursor in the synthesis of new-generation fluorinated pesticides and herbicides with enhanced efficacy.
• Organic Light-Emitting Diode (OLED) Materials: Acts as an electron-transport or emissive layer component in the fabrication of advanced display technologies.
• Polymer & Material Science: Incorporated into polymers to impart specific optical, electronic, or surface properties.
• Chemical Biology Tool: Utilized in activity-based protein profiling (ABPP) and other biochemical assays as a fluorogenic tag.

Basic Information

Product Name	7-Hydroxy-4-(Trifluoromethyl)Coumarin
CAS No.	575-03-1
Molecular Formula	C10H5F3O3
Molecular Weight	230.14 g/mol
Synonyms	4-(Trifluoromethyl)-7-hydroxycoumarin; 7-Hydroxy-4-trifluoromethylcoumarin; 7-Hydroxy-4-(trifluoromethyl)-2H-1-benzopyran-2-one; 4-Trifluoromethylumbelliferone; HFC; 7-Hydroxy-4-trifluoromethyl-2H-chromen-2-one
EINECS	209-379-5

Quality Control

Our 7-Hydroxy-4-(Trifluoromethyl)Coumarin is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	245 - 250 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.