Description

(2R,3R)-5,7-Dihydroxy-2-(4-Hydroxyphenyl)-3-[(2S,3R,4R,5S,6S)-3,4,5-Trihydroxy-6-Methyl-Oxan-2-Yl]Oxy-Chroman-4-One is a high-purity flavonoid glycoside, widely recognized as a key reference standard and active pharmaceutical ingredient (API) intermediate. This compound is valued for its precise stereochemistry and consistent quality, which are critical for research and development in advanced life sciences. It is essential for pharmaceutical manufacturers, nutraceutical formulators, and analytical laboratories requiring a reliable standard for quality control and method validation.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and impurity profiling of related drug substances and botanical extracts in HPLC and LC-MS analysis.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a critical chiral building block in the synthesis of advanced therapeutic agents targeting oxidative stress and inflammation.
• Nutraceutical & Dietary Supplement Research: Employed in the development and standardization of high-value flavonoid-based supplements, ensuring potency and label claim verification.
• Biochemical & Pharmacological Research: Utilized in in vitro and in vivo studies to investigate antioxidant, anti-inflammatory, and metabolic activities.
• Cosmeceutical Development: Incorporated into research for advanced skincare formulations aimed at providing antioxidant protection and improving skin health.
• Food & Beverage Analysis: Acts as an analytical standard for the quantification of flavonoids in food products, beverages, and raw agricultural materials for quality assurance.

Basic Information

Product Name	(2R,3R)-5,7-Dihydroxy-2-(4-Hydroxyphenyl)-3-[(2S,3R,4R,5S,6S)-3,4,5-Trihydroxy-6-Methyl-Oxan-2-Yl]Oxy-Chroman-4-One
CAS No.	572-31-6
Molecular Formula	C22H22O11
Molecular Weight	462.40 g/mol
Synonyms	Taxifolin 3-O-α-L-Rhamnopyranoside; Dihydroquercetin 3-O-α-L-Rhamnoside; Astilbin; (2R,3R)-Astilbin; Engelitin; 3,5,7,3',4'-Pentahydroxyflavanone 3-rhamnoside; Taxifolin-3-O-rhamnoside; Dihydroquercetin 3-rhamnoside
EINECS	Contact for details

Quality Control

Our (2R,3R)-5,7-Dihydroxy-2-(4-Hydroxyphenyl)-3-[(2S,3R,4R,5S,6S)-3,4,5-Trihydroxy-6-Methyl-Oxan-2-Yl]Oxy-Chroman-4-One is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and residual solvent screening to ensure compliance with ICH guidelines and customer-specific requirements. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and opened under controlled conditions to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Specific Rotation	Contact for details
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH Q3C
Chiral Purity (Chiral HPLC)	≥99.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.