Description

Androst-4-Ene-3,11-Dione is a key steroid intermediate and a derivative of androstenedione. This compound is valued for its role as a versatile building block in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily required by pharmaceutical R&D laboratories and manufacturers engaged in the production of corticosteroids, hormone therapies, and other specialized steroid compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of corticosteroid drugs such as cortisone and hydrocortisone.
• Hormone Research: Used as a reference standard and starting material in biochemical research related to androgen and steroid hormone pathways.
• API Synthesis: Serves as a building block for manufacturing more complex steroid-based Active Pharmaceutical Ingredients (APIs).
• Biochemical Studies: Employed in enzymatic studies, particularly those investigating 11-β-hydroxylase and other steroidogenic enzymes.
• Reference Standard: Utilized in analytical laboratories for method development and quality control testing of steroid products.

Basic Information

Product Name	Androst-4-Ene-3,11-Dione
CAS No.	570-29-6
Molecular Formula	C19H26O2
Molecular Weight	286.41 g/mol
Synonyms	11-Oxoandrostenedione; 4-Androstene-3,11-dione; Adrenosterone; Reichstein's Substance G; 11-Ketoandrostenedione; 3,11-Diketo-4-androstene; 11-Oxo-4-androstene-3,17-dione
EINECS	209-327-0

Quality Control

Our Androst-4-Ene-3,11-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets high-purity standards suitable for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider packaging under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.